Schematic illustration of activated and inhibited Wnt/β-catenin pathway. “WNT ON condition�? Upon ligation of Wnts to their receptors made up of frizzled proteins and LRP5/six, the cytoplasmic protein DVL is activated and induces the suppression of GSK3β. Subsequently, stabilized β-catenin translocates to the nucleus and binds to TCF/LEF transcription things https://chaunceyu577dnw0.wikinarration.com/user