CYP3A4 inducers could increase the formation in the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Carefully observe clients using ifosfamide with CYP3A4 inducers for toxicities and consider dose adjustment. pentobarbital will lessen the extent or influence of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. pentobarbital wil... https://queeselnembutal04826.thechapblog.com/30395875/an-unbiased-view-of-what-type-of-drug-is-nembutal