[114] Activation from the ECS system in MS (and EAE) appears to limit neuronal problems by downregulation of cannabinoid receptors inhibiting GABA synapses as a protective motion to reduce neuronal excitotoxic destruction. Upregulation of endocannabinoid tone protects neurons from excitotoxicity in parallel having a therapeutic result within a mouse model https://thcawhatdoesitdo34443.humor-blog.com/31948243/cannabis-strains-fundamentals-explained