2. Histamine Receptor Antagonism: Some sedatives, like antihistamines, exert their sedative effects by blocking histamine receptors in the brain, significantly H1 receptors. Histamine performs a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness. Health supplements: Various health supplements — like valerian root, melatonin, passionflower, https://sedatives-drugs32086.targetblogs.com/33563392/sedative-medications-for-anxiety-best-options-for-relief